New Model Can Help Understand How Endometriosis-Associated Ovarian Cancer Develops
Researchers from Japan and the US developed a new mouse model in collaboration, that can be useful to better understand how endometriosis-associated ovarian cancer develops. This new model can help to assess new treatment options for both diseases. The team…
Key Points Lay SummaryResearchers Develop New Mouse Model of Endometriosis
Researchers from China developed a new mouse model to study endometriosis that could help researchers better understand the molecular mechanisms that lead to the development of endometriosis and develop potential new treatments for the disease. Even though many animal models…
Key Points Lay SummaryChasing gold to find endometriosis.
Endometriosis is a disease that doesn’t have a proper preoperative diagnostic test. Thus, animal models to study endometriosis are vital to show the effects of drugs and the effects of the disease on the body. In the study conducted by…
Key Points Lay SummaryPotential New Approach to Treat Endometriosis
Inhibiting ribosome biogenesis could be a potential therapeutic approach for endometriosis according to a new study published in the scientific journal Biomedicines. Ribosome biogenesis plays a key role in protein homeostasis during cell growth and division. Previous research has shown…
Key Points Lay SummaryNew Signaling Pathway Could Be Crucial in the Development of Endometriosis
RAMP1 signaling is crucial for growth and blood and lymphatic vessel formation in endometrial tissue, according to a new study published in the Journal of Cellular and Molecular Medicine. This suggests that blocking RAMP1 could be a new way to…
Key Points Lay SummaryThe reason for lower BMI and less body fat in women with endometriosis.
Zolbin et al. from the Department of Obstetrics and Gynecology of Yale School of Medicine, New Haven, USA, recently published the results of their prospective controlled research on adipocyte alterations in endometriosis, in the journal "Reproductive Biology and Endocrinology". Endometriosis can…
Key Points Lay SummaryReducing the Risk of Recurrence After Endometriosis Surgery
The use of compounds called NF-κB inhibitors and β-blockers before and after endometriosis surgery may reduce the risk of the disease recurring, according to a study conducted in a mouse model. According to the study published in the journal Reproductive…
Key Points Lay SummaryStudy Sheds Light on the Molecular Mechanism of Endometriosis Development
A protein called transforming growth factor-beta1 (TGF-B1) enhances the capacity of endometriotic cells or cells that make up the lining of the uterus to migrate, invade, and colonize other areas in the body. This is according to a study published…
Key Points Lay SummaryAn Alternative Medical Approach to Treat Endometriosis?
Molecules that act on a protein called SRC-1 could constitute a new medical tool to treat endometriosis, according to a study published in the Journal of Endocrinology. SRC-1 makes certain parts of DNA more accessible therefore increasing gene expression or…
Key Points Lay SummaryNew Target for Endometriosis Treatment?
NR4A1 could be a novel target for the treatment of endometriosis, according to a study published in the scientific journal Cell Physiology and Biochemistry. NR4A1 is a receptor protein involved in cell division, inflammation, and programmed cell death. The development…
Key Points Lay SummaryCould Gabapentin Make my Pain Go Away?
Gabapentin could effectively reduce endometriosis-associated pain, according to a new study published in the Journal of Pain Research. The study that was conducted in mice and endometriotic tissues from patients suggests that certain proteins present on the surface of cells…
Key Points Lay SummaryPotential New Target to Treat Endometriosis?
Special cells called myeloid-derived suppressor cells (MDSC) could be playing a role in the development of endometriosis, suggests a study published in the European Journal of Immunology. These cells could, therefore, be targeted by novel therapeutic agents to treat endometriosis. …
Key Points Lay SummaryPlant Compound May Protect Against Endometriosis
Marrubiin, a compound derived from a plant in the mint family called white horehound may have protective effects against endometriosis, according to a study published in the journal Molecular Medicine Reports. Marrubiin is the main analgesic, or painkiller compound found…
Key Points Lay SummaryFemale Sex Hormone Necessary but not Enough to Cause Endometriosis
Estrogen, the primary female sex hormone may be necessary but is not enough to induce endometriosis, found a study published in the Journal of Bioscience. This finding is important because it can help scientists better understand factors that cause endometriosis…
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